Table 4.
Comparison of Endophthalmitis due to Corynebacterium species studies
| Current Study | Joseph et al.LV Prasad Eye Institute45 | |
|---|---|---|
| Antibiotic | No. of Patients (%) | No. of Patients (%) |
| Clinical setting | ||
| Post-cataract surgery | 6 (60%) | 5 (31%) |
| Post-PKP surgery | 2 (20%) | 1 (6%) |
| Post-Glaucoma procedures | 2 (20%) | - |
| Trauma | - | 10 (63%) |
| Initial treatment | ||
| Vitreous tap + antibiotics | 5 (50%) | - |
| PPV + antibiotics | 5 (50%) | 16a (100%) |
| Presenting VA | ||
| LP or Worse | 3 (30%) | 7 (44%) |
| HM or Better | 7 (70%) | 9 (56%) |
| Final VA | ||
| ≥20/400 | 6 (60%) | 11 (69%) |
| <20/400 | 4 (40%) | 5 (31%) |
| Antibiotic Susceptibility | ||
| Vancomycin | 10/10 (100%) | 16/16 (100%) |
| Gentamicin | 6/7 (86%) | 11/14 (79%) |
| Ceftazidime | 2/2 (100%) | 1/10 (10%) |
| Fluoroquinolones | ||
| Ciprofloxacin | 6/8 (75%) | 12/16 (75%) |
| Gatifloxacin | 1/2 (50%) | 15/16 (94%) |
| Moxifloxacin | 1/2 (50%) | 7/9 (78%) |
HM = hand motion, LP = light perception, PKP = penetrating keratoplasty, No. = number, PPV = pars plana vitrectomy, VA = visual acuity, UK = unknown,
a
Includes nine patients treated with PPV and intravitreal antibiotics as well as seven patients treated with pars plana lensectomy along with pars plana vitrectomy and intravitreal antibiotics.