Figure 2. The sizes and fold changes of all alleles found in original and regenerated limbs in this study.

(A) Pie chart depicting numbers of all alleles identified in original limbs binned by RPM. The majority of alleles detected are low frequency (i.e., represent less than 1.6% of all sequence reads in limb). (B) Histograms depicting the log of fold change for all alleles after limb regeneration. The majority of low frequency alleles are retained.