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. 2017 Sep 7;2(17):e95177. doi: 10.1172/jci.insight.95177

Figure 5. REV-ERB agonist ameliorate cardiac dysfunction in pressure-overload models.

Figure 5

(A–D) Six-week followup of 27-gauge TAC performed on 8-week-old mice, vehicle, or SR9009, which were given daily starting 1 day after surgery. n = 5. (A) Ejection fraction (EF), *P < 0.05. (B) Fraction shortening (FS), *P < 0.05. (C) Left ventricle internal diameter end diastole. (D) Left ventricle internal diameter end systole. *P < 0.05. Statistical differences were determined by 2-tailed Student’s t test. Data are presented as mean ± SEM. Multiple comparison is corrected for by using Holm-Sidak method, with α = 0.05.