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. 2017 Sep 21;2(18):e95352. doi: 10.1172/jci.insight.95352

Figure 4. Acute uncomplicated malaria is associated with an increased PD-L1/CD86 ratio on all monocyte subsets.

Figure 4

Ratios of cell surface expression of PD-L1/CD86 on the (A) classical, (B) intermediate, and (C) nonclassical monocyte subsets for samples from cases of acute malaria, 6-week recovery samples (n = 23 pairs), and samples from healthy child controls (n = 17) are indicated on the y axes. Bars represent the median values with interquartile ranges. Wilcoxon matched-pairs rank test was used to compare acute malaria samples to 6-week recovery samples. Kruskal-Wallis test was used to compare healthy children to acute malaria samples and 6-week recovery samples. **P < 0.01, ***P < 0.001, ****P < 0.0001. iMFI, integrated mean fluorescence intensity; PD-L1, programmed death-ligand 1.