Table 2.

PK parameters of the key compounds^a

Code	Tmax (h)	Cmax (μM)	AUC 0–t (μM h)	AUC 0–∞ (μM h)	MRT (h)	t1/2 (h)
7a	0.42	0.62	1.55	1.58	3.55	4.69
7b	1.00	0.79	2.32	2.36	4.47	3.39

^aPK parameters were calculated in rats after single oral dosing of 25 mg kg⁻¹, (n = 3) by non-compartmental analysis using WinNonlin, version 5.3