Table 4.
Comparison of TLR7 rs179009 distributions among three groups of patients who had confirmed CHB, LC and HCC.
| rs179009 | CHB, N(%) | LC, N(%) | HCC, N(%) | Pa | Pb/OR(95%CI) | Pc/OR(95%CI) |
|---|---|---|---|---|---|---|
| Male | N = 147 | N = 148 | N = 124 | |||
| A | 128(87.1) | 123(83.1) | 96(77.4) | Ref. | Ref. | Ref. |
| G | 19(12.9) | 25(16.9) | 28(22.6) | 0.012 | 0.339/0.730 (0.383–1.393) | 0.029/2.435 (1.094–5.419) |
| Female | N = 103 | N = 71 | N = 19 | |||
| AA | 70(68) | 48(67.6) | 12(63.2) | Ref. | Ref. | Ref. |
| AG | 30(29.1) | 20(28.2) | 6(31.6) | 0.910 | 0.935/1.029 (0.524–2.019) | 0.777/0.857 (0.294–2.497) |
| GG | 3(2.9) | 3(4.2) | 1(5.3) | 0.540 | 0.978/0.686 (0.133–3.542) | 1.000/0.514 (0.049–5.363) |
| Allele | ||||||
| A | 170(82.5) | 116(81.7) | 30(78.9) | Ref. | Ref. | Ref. |
| G | 36(17.5) | 26(18.3) | 8(21.1) | 0.656 | 0.842/0.945 (0.541–1.649) | 0.598/0.794 (0.336–1.874) |
aP value of nonparametric Kruskal Wallis test among three groups of patients with CHB, LC and HCC.
bP value was adjusted for age by logistic regression between patients with LC and CHB.
cP value was adjusted for age by logistic regression between patients with HCC and CHB.