Figure 5.

Kinetic simulations data. Model was initialized using ligand concentrations from proteomic analysis (Table 1) and kinetic rates listed in Table 2. The ECM:integrin binding pairs fibronectin:αvβ3, von Willebrand factor: αvβ3, and collagen I:α1β1 are shown, with binding curves and percent occupancy for fully occupied single divalent receptors (C _d) and aggregated receptor pairs (A _dd).