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. 2017 Sep 29;7:12425. doi: 10.1038/s41598-017-09635-x

Figure 5.

Figure 5

(A) Brain activity during rectal distention associated with individual ACTH-AUC responses to CRH between patients with IBS and control subjects. (B) Scatter plot and regression of Eigenvariates during rectal distention (versus no distention) and ACTH area under the curve (ACTH-AUC) in patients with IBS versus control subjects for the right anterior cingulate cortex. Abbreviations: ACC, anterior cingulate cortex; ACTH-AUC, adrenocorticotropic hormone-area under the curve; CRH, corticotropin-releasing hormone; IBS, irritable bowel syndrome.