Figure 6.
SIRT7 promotes osteosarcoma cell metastasis in vivo. (A) The total numbers of mice with liver distant metastasis at 30 days after injection of SJSA-1-shSIRT7 or its control cells into tail vein. (B) Representative images of liver tissues measured by H&E stain with injection of SJSA-1-shSIRT7 or its control cells into tail vein. (C) The numbers of metastatic foci per section in liver of individual mouse with injection of SJSA-1-shSIRT7 or its control cells into tail vein. (D) The total numbers of mice with liver distant metastasis at 30 days after injection of D-17-SIRT7 or its control cells into tail vein. (E) Representative images of liver tissues measured by H&E stain with injection of D-17-SIRT7 or its control cells into tail vein. (F) The numbers of metastatic foci per section in liver of individual mouse with injection of D-17-SIRT7 or its control cells into tail vein. **P < 0.01 (in C and F) is based on Student’s t-test. Error bars indicate standard deviation.