Table 2.
Top 30 cellular pathways influenced by dysregulated exosomes miRNAs
| KEGG pathway | p-value | Genes | miRNAs |
|---|---|---|---|
| MicroRNAs in cancer | 4.70E-42 | 94 | 11 |
| Proteoglycans in cancer | 5.98E-12 | 110 | 11 |
| Renal cell carcinoma | 2.70E-09 | 45 | 11 |
| Hepatitis B | 4.18E-08 | 74 | 11 |
| Pancreatic cancer | 3.70E-07 | 46 | 11 |
| Prion diseases | 8.29E-07 | 13 | 8 |
| Adherents junction | 8.29E-07 | 43 | 9 |
| Pathways in cancer | 8.29E-07 | 189 | 11 |
| Thyroid hormone signaling pathway | 1.18E-06 | 65 | 11 |
| Colorectal cancer | 2.01E-06 | 41 | 11 |
| Glioma | 2.01E-06 | 39 | 11 |
| Chronic myeloid leukemia | 6.23E-06 | 46 | 11 |
| Protein processing in endoplasmic reticulum | 1.20E-05 | 91 | 11 |
| Fatty acid biosynthesis | 1.27E-05 | 6 | 6 |
| FoxO signaling pathway | 2.28E-05 | 75 | 11 |
| Endometrial cancer | 2.28E-05 | 34 | 11 |
| Prostate cancer | 2.28E-05 | 54 | 11 |
| Non-small cell lung cancer | 2.45E-05 | 36 | 11 |
| Hippo signaling pathway | 3.24E-05 | 76 | 11 |
| ErbB signaling pathway | 6.07E-05 | 48 | 12 |
| Phosphatidylinositol signaling system | 6.10E-05 | 45 | 10 |
| Cell cycle | 9.15E-05 | 65 | 10 |
| Lysine degradation | 0.000108681 | 25 | 8 |
| TGF-beta signaling pathway | 0.000118299 | 40 | 10 |
| Viral carcinogenesis | 0.000428011 | 80 | 11 |
| Focal adhesion | 0.000587465 | 104 | 11 |
| p53 signaling pathway | 0.000610132 | 42 | 6 |
| Bacterial invasion of epithelial cells | 0.000740575 | 41 | 9 |
| HIF-1 signaling pathway | 0.001817139 | 56 | 10 |
| Neurotrophin signaling pathway | 0.002456577 | 63 | 11 |