G>T transition at rs8957 E[GAG]233D[GAU] alters the subcellular distribution pattern of SLC2A4RG. (A)Subcellular localization of SLC2A4RG-rs8957-EGFP polymorphism expressed transiently in HeLa cells. Scale bars, 15 μm. (B) Percentage of cells with nuclear speckles after Hela cells were transiently transfected with expression plasmids of SLC2A4RG-rs8957-G-EGFP and SLC2A4RG-rs8957-T-EGFP. Values are means ± SD. All images were obtained at a magnification of × 630 (A). *, p < 0.05; **, p < 0.01, ***, p < 0.001.