Figure 2.

Effects of cisplatin on apoptosis in SKOV3 and hey cell lines. Apoptosis was evaluated with PE Annexin V and 7-ADD staining in SKOV3 and hey cells after treatment with cisplatin (2.5 uM, 5 uM and 10 uM) for 24 hours. (A and D) Representative dot plots illustrating the data near the mean of the groups in (B and E) *, P < 0.05 and **, P < 0.01 for comparisons between cells treated with cisplatin and untreated cells. (C and F) Western blotting analysis of cleaved-caspase 3, cleaved PARP, Bax, Bcl-XL and Bcl-2. Western blotting of GAPDH was included as aloading control.