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. 2017 Sep 15;9(9):4059–4070.

Figure 6.

Figure 6

MiR-139 and CXCR4 levels are highly associated with the prognosis of T-ALL patients. A. qPCR analysis of miR-139 levels in T-ALL samples compared with those from healthy donors (HD) (n = 20). U6 was used as the internal control. B. mRNA levels of CXCR4 in T-ALL and HD specimens were measured by qPCR assays (n = 20). GAPDH was used as the endogenous control. C. Correlation between CXCR4 level and miR-139 expression in T-ALL specimens (n = 20). D. Five-year overall survival rate of T-ALL patients with miR-139 low expression and CXCR4 high level (n = 29) and the patients with miR-139 high expression and CXCR4 low level (n = 11). All data are shown as mean ± SD of three separate experiments. *P < 0.05 vs. HD group; **P < 0.01 vs. HD group. HD: healthy donors.