Figure 1.

Fe ion irradiation induces a more pronounced and persistent transcriptional response in ECs in comparison to X-ray irradiation. Venn diagrams indicate the number of differentially expressed genes after exposure to a single 2.0 Gy dose of X-rays (A) or Fe ions (B). The gene expression changes after low and high LET irradiation are compared on day 1 (C) and on day 7 (D). Changes are compared gene expression in sham irradiated cells, as described in section Materials and Methods (N = 3, n = 12).