Table 4.

Differently expressed proteins after Fe ion and X-ray irradiation are mainly involved in cell death, cell cycle and cell-cell signaling.^*

	X-rays description of molecular function	−log10 (p-value)	Fe ions description of molecular function	−log10 (p-value)
Day 1	Cell Death and Survival	6.8	Cell Death and Survival	10.3
	Cell Morphology	6.8	Cellular Growth and Proliferation	5.5
	Cell-To-Cell Signaling and Interaction	6.7	Cell Morphology	4.4
	Cellular Movement	6.5	Cellular Development	4.4
	Cellular Growth and Proliferation	6.1	Cellular Function and Maintenance	4.4
	Cellular Assembly and Organization	5.7	Cellular Assembly and Organization	4.4
	Cellular Compromise	5.7	Cell-To-Cell Signaling and Interaction	4.3
	DNA Replication. Recombination. and Repair	4.8	Cell Cycle	3.9
	Cellular Development	4.7	Cellular Movement	3.9
	Cell Cycle	4.1	Post-Translational Modification	3.8
Day 7	Cell Death and Survival	8.5	Cell Death and Survival	14.9
	Cellular Movement	6.4	Cell-To-Cell Signaling and Interaction	9.2
	Cell Morphology	6.2	Cellular Movement	7.6
	Cellular Growth and Proliferation	5.8	Cellular Growth and Proliferation	7.0
	Cell Cycle	5.4	Cell Cycle	6.5
	Cellular Function and Maintenance	5.0	Cellular Development	6.3
	Cell-To-Cell Signaling and Interaction	4.9	Cellular Function and Maintenance	5.7
	DNA Replication. Recombination. and Repair	4.8	Cell Morphology	5.3
	Cellular Development	4.3	Cellular Assembly and Organization	5.2
	Gene Expression	3.9	Protein Degradation	4.5

^*Protein ontology analysis was performed on differentially expressed proteins in irradiated vs. sham-irradiated ECs (n = 3). Table shows the top 10 molecular functions identified on day 1 (top) or day 7 (bottom) in ECs after a 2 Gy irradiation with X-ray (left) or Fe ions (right).