Figure 2.

Frequency of γδ T cells is negatively correlated with CD8 T cell activation in primary HIV infection (PHI). (A) Relationship between the frequency of γδ T cells and the proportion of CD38⁺ γδ T cells in viremic patients [PHI and untreated chronic HIV infection (UT-CHI)]. (B,C) Correlation analysis between the frequency of γδ T cells and the proportion of CD38⁺HLA-DR⁺ CD8 T cells in PHI and UT-CHI. (D,E) Correlation between the frequencies of CD38⁺ γδ T cells and CD38⁺CD8 T cells in PHI or UT-CHI. Spearman rank correlation coefficients (r) and corresponding p values are indicated in each panel; p-values are indicated as significant when <0.05; ns, non-significant.