Table 1.

TAV vs. BAV aortopathy.

Tricuspid aortopathy	Bicuspid aortopathy
EPIDEMIOLOGY
Rare Onset later in life (>70 years) Association with hypertension and other risk factors for aortopathy Lower correlation with severity of aortic stenosis	Frequent in BAV population Onset earlier in life (<70 years) Reduced association with risk factors for aortopathy Moderate correlation with severity of aortic stenosis
MACROSCOPIC AORTOPATHY
Commonly symmetric dilation of the tubular ascending aorta Lower prevalence of aortic stenosis Aortopathy and dissection rarely occurs after AVR	Higher prevalence of aortic root aneurysm Higher prevalence of aortic dilation Higher prevalence of dilation of the outer curve of the ascending aorta Associated with coarctation of the aorta Reported association with type of cusp fusion Common transverse aortic stenosis jet Aortopathy and dissection occasionally occurs after AVR
MICROSCOPIC AORTOPATHY
Severe elastin degeneration Cystic degeneration of the media Inflammatory response often present	Normal fiber architecture Loss of smooth muscle cells with apoptosis Medial degeneration and lower fibrillin content