Table 3.

Brain regions activated during tasting monosodium glutamate solution.

Region	Hemisphere	MNI coordinates			Z-score	Voxels	PFWE-value
		x	y	z
All participants
Precentral/postcentral gyrus	L	−60	−12	30	7.61	998	<0.001
	L	−44	−18	38	6.54		<0.001
	L	−62	6	22	5.57		<0.001
Precentral/postcentral gyrus	R	56	−6	38	7.00	1,891	<0.001
	R	54	−6	30	7.00		<0.001
	R	64	4	22	6.86		<0.001
Superior frontal gyrus	L	−8	−6	60	6.53	487	<0.001
	R	8	0	60	6.45		<0.001
Insula	R	34	18	8	6.25	155	<0.001
	R	38	10	2	5.66		<0.001
Cerebellum	L	−36	−62	−34	5.94	126	<0.001
	L	−12	−66	−28	5.70		<0.001
	L	−20	−68	−32	5.54		<0.001
Middle frontal gyrus	R	32	42	24	5.93	55	<0.001
BN
Precentral/postcentral gyrus	L	−58	−14	30	6.94	1,085	<0.001
	L	−44	−18	40	6.13		<0.001
	L	−64	−8	18	5.56		<0.001
Precentral/postcentral gyrus/inferior frontal gyrus/insula	R	50	−8	30	6.22	3,454	<0.001
	R	32	42	26	6.12		<0.001
	R	56	−6	40	5.96		<0.001
Supplementary motor area/middle frontal gyrus	R	10	0	62	5.83	956	<0.001
	L	−4	10	50	5.52		0.001
	L	−2	−2	60	5.36		0.001
Superior frontal gyrus/middle frontal gyrus	L	−30	46	20	5.48	333	0.001
	L	−26	48	6	4.74		0.018
Cerebellum	L	−36	−62	−34	5.15	252	0.003
	L	−12	−64	−28	4.86		0.011
HW
Precentral/postcentral gyrus	L	−60	−12	30	5.94	319	<0.001
Precentral/postcentral gyrus	R	58	−4	38	5.51	908	0.001
	R	62	4	20	5.44		0.001
	R	30	−4	22	5.40		0.001

Activated brain regions are defined by thresholding at P < 0.001 (for all participants) or P < 0.05 (for each group) with FWE correction at peak level, and q < 0.05 with false discovery rate correction at cluster level.

BN, patients with bulimia nervosa; FWE, familywise error; HW, healthy women participants; MNI, Montreal Neurological Institute.