Table 4.

Group differences of BOLD signal responses to monosodium glutamate stimuli.

Region	Hemisphere	MNI coordinates			Z-score	Voxels	PSVC-value
		x	y	z
BN > HW
Insula	R	36	−4	8	4.27	47	0.002
Anterior cingulate cortex	0	34	12	4.06	150	0.006
HW > BN
None

Small volume corrections (P < 0.05, familywise error corrected at voxel level) were applied after a priori whole-brain analysis thresholded at P < 0.001 uncorrected for multiple comparisons and more than 54 voxels, which was computed as the number of expected voxels per cluster.

BN, patients with bulimia nervosa; BOLD, blood-oxygen-level dependent; HW, healthy women participants; MNI, Montreal Neurological Institute; SVC, small volume correction.