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. 2017 Sep 29;15:179. doi: 10.1186/s12957-017-1239-8

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Representative metastatic tumor with strong PpIX fluorescence (case 5). a Gadolinium-enhanced T1-weighted MRI showing a left frontal metastatic tumor in a rectal cancer patient. b The resected tumor was sectioned and observed under the fluorescence mode. The tumor was divided into fluorescing (F) and nonfluorescing (N) sections. c HE staining of the fluorescent section shows typical adenocarcinoma with tubular formation (×200 magnification). d HE staining of the nonfluorescing section shows the same histopathological findings as the fluorescent section. There are no necrotic changes (×200 magnification)