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. 2017 Sep 29;8:215. doi: 10.1186/s13287-017-0673-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Alterations of molecules and specific markers of cardiogenic differentiation after inhibition of the HIF-1α/apelin/APJ axis. (a) Western blot and (b) qRT-PCR analysis of the molecules in the HIF-1α/apelin/APJ axis after relevant siRNA interference. c Changes of cardiogenic differentiation specific genes including α-SA and cTnT after the blockage of the HIF-1α/apelin/APJ axis. **p < 0.01 vs normoxia, ## p < 0.01 vs HP, ††p < 0.01 vs NC. HP: hypoxia preconditioning, HIF: hypoxia-inducible factor, apelin: ligand for putative receptor protein related to angiotensin receptor AT1, APJ: putative receptor protein related to angiotensin receptor AT1, NC negative control