Table 2.
Effect of aqueous fraction of Moringa stenopetala on radiant tail flick latency and maximum possible protection(%)
| Latency (sec) and maximum possible protection (%) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Groups | 0 time | 30 min | % | 60 min | % | 90 min | % | 120 min | % |
| DW | 2.18 ± 0.034 | 2.10 ± 0.1 | – | 2.18 ± 0.2 | – | 2.26 ± 0.2 | – | 2.15 ± 0.1 | – |
| MO | 2.23 ± 0.034 | 9.23 ± 0.09a3d3 | 90.2 | 8.87 ± 0.21a3d3 | 85.4 | 7.44 ± 0.09a3d3 | 67.0 | 7.05 ± 0.06a3 | 62.1 |
| AF 100 | 2.23 ± 0.052 | 3.00 ± 0.08a3b3d1 | 10.0 | 3.67 ± 0.17a2e3b3 | 18.6 | 4.49 ± 0.19e3a3d3 | 29.2 | 5.71 ± 0.09a3b3d3e3 | 44.8 |
| AF 200 | 2.33 ± 0.049 | 3.18 ± 0.11a3e3 | 11.1 | 3.87 ± 0.07a3b3e3 | 29.2 | 5.01 ± 0.11a3b3e3 | 34.9 | 7.7 ± 0.22a3c3 | 70.1 |
| AF 400 | 2.13 ± 0.044 | 3.61 ± 0.1a3b3c3d3 | 18.9 | 4.79 ± 0.09a3b3c3d3 | 44.8 | 6.26 ± 0.05a3c3d3 | 70.1 | 7.71 ± 0.27a3c3 | 73.6 |
Values are expressed as Mean ± S.E.M (n = 6); aagainst the control, bagainst the standard drug, cagainst AF100, dagainst AF200, eagainst AF400, 1 P < 0.05, 2 P < 0.01, 3 P < 0.001; AF refers to aqueous fraction of Moringa stenopetala, MO morphine; and DW stands for Distilled Water. Control received distilled water (10 ml/kg), whereas standard received Morphine (20 mg/kg) orally; Numbers refers to doses in mg/kg