Table 3.
Meta-analysis results.
| Pooled Analysis | Heterogeneity | Publication Bias | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Outcome | Effect Size | CI | p Value | Q | I2 | p Value | T2 | T | Egger’s | Begg and Mazdumdar’s | Fail-Safe | Rosenthal | ||
| T | p Value | Z | p Value | No. | No. | |||||||||
| RCTs Low-FODMAP vs. Traditional IBS Diet (k = 3) [29,30,36] | ||||||||||||||
| Abdominal Pain | 0.44 (OR) | (0.26; 0.79) | 0.006 | 2.43 | 17.81 | 0.296 | 0.05 | 0.23 | −0.19 | 0.877 | 0.52 | 0.602 | 4 | 25 |
| Bloating | 0.32 (OR) | (0.15; 0.66) | <0.0001 | 1.97 | 0.00 | 0.374 | 0.00 | 0.00 | −1.21 | 0.439 | −0.52 | 0.602 | 11 | 25 |
| Stool Consistency | 0.24 * | (−0.13; 0.61) | 0.209 | 3.07 | 34.84 | 0.216 | 0.04 | 0.19 | −0.02 | 0.989 | −0.52 | 0.602 | 0 | 25 |
| Stool Frequency | −0.54 * | (−0.83; −0.24) | <0.0001 | 1.67 | 0.00 | 0.434 | 0.00 | 0.00 | −5.74 | 0.110 | −1.57 | 0.117 | 8 | 25 |
| RCTs Low-FODMAP vs. Medium/High FODMAP (k = 3) [25,26,53] | ||||||||||||||
| Abdominal Pain | 0.17 (OR) | (0.08; 0.34) | <0.0001 | 1.14 | 0.00 | 0.567 | 0.00 | 0.00 | −4.69 | 0.150 | −1.54 | 0.018 | 17 | 25 |
| Bloating | 0.13 (OR) | (0.04; 0.40) | <0.0001 | 4.11 | 51.37 | 0.128 | 0.51 | 0.72 | −8.89 | 0.071 | −0.57 | 0.017 | 66 | 40 |
| Cohort Studies (k = 6) [34,54,55,56,57,58] | ||||||||||||||
| Abdominal Pain | −0.59 * | (−0.76; −0.42) | <0.0001 | 2.85 | 0.00 | 0.723 | 0.00 | 0.00 | −2.45 | 0.070 | −1.69 | 0.091 | 66 | 40 |
| Bloating | −0.64 * | (0.82; −0.46) | <0.0001 | 1.20 | 0.00 | 0.878 | 0.00 | 0.00 | −1.13 | 0.342 | −0.98 | 0.327 | 59 | 40 |
CI: Confidence Interval; OR: Odds Ratio; * Cohen’s d.