Table 3.
Concentration of TNF-α and IL-10 (pg/mL; mean ± standard deviation) of animals with diabetes and/or periodontal disease treated or not treated with β-glucan at a dose of 30 mg/kg/day for 28 days.
| Diabetes | Periodontal Disease | β-Glucan | |
|---|---|---|---|
| − | + | ||
| TNF-α | |||
| − | − | 2.61 (0.95) Aa | 2.81 (0.39) |
| − | + | 4.02 (0.64) Ab | 3.33 (0.92) |
| + | − | 4.29 (1.57) Ba | 3.79 (0.90) |
| + | + | 7.11 (1.51) Bbx | 3.05 (0.79) y |
| IL-10 | |||
| − | − | 24.62 (3.74) a | 20.69 (5.09) a |
| − | + | 35.56 (7.03) bx | 28.40 (4.98) by |
| + | − | 27.41 (2.70) a | 26.68 (3.51) |
| + | + | 37.45 (8.76) bx | 29.04 (5.86) y |
A,B Different letters in the columns indicate a significant difference between the groups with and without diabetes (p < 0.05); a,b Different letters in the columns indicate a significant difference between the groups with and without periodontal disease (p < 0.05); x,y Different letters in the rows indicate a significant difference between the groups with and without β-glucan (p < 0.05).