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. 2017 Sep 14;9(9):1018. doi: 10.3390/nu9091018

Figure 2.

Figure 2

Effects of the HFC diet on the activation of the TNF-α/NF-κB pathway. ELISA analysis to measure the TNF-α serum levels in rats (A). Western blot analysis of the protein expression levels in liver homogenates or nuclear fragments (B,C). DNA-binding activity of NF-κB p65 (D). n = 6/group. The values in parentheses represent the fold changes compared with the respective control. a p < 0.05 vs. the respective control group; b p < 0.05 vs. WKY control group; c p < 0.05 vs. the fold change in WKY. TNF-α: tumor necrosis factor-α; IKKβ: inhibitor of κB kinase β; IκBα: inhibitor of κB-α; NF-κB: nuclear factor-κB; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; TBP: TATA-binding protein; Con.: control.