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. 2017 Sep 26;10:307. doi: 10.3389/fnmol.2017.00307

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Copyright © 2017 Wolstenholme, Mahmood, Harris, Abbas and Miles.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Recognition memory was impaired in adult mice after binge ethanol in adolescence. After a 5-min delay between training and testing (A), ethanol-exposed DBA/2J adult mice (n = 6–11/group) had a zero or negative discrimination index, indicating a failure to recognize a novel object, or failure to remember a familiar object. After a 1-h delay (B), DBA/2J adult female mice had a trend to a lower discrimination index. Data is presented as mean +/– SEM. ^∗p < 0.05, main effect of treatment by Two-Way ANOVA. ˆp = 0.07, a trend for a significant effect of treatment.