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. 2017 Sep 26;11:307. doi: 10.3389/fncel.2017.00307

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Copyright © 2017 Forero, Rivero, Wäldchen, Ku, Kiser, Gärtner, Pennington, Waider, Gaspar, Jansch, Edenhofer, Resink, Blum, Sauer and Lesch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cdh13 in embryonic mouse brain at selected developmental stages. (A) Cdh13 immunoreactivity is prominent in the hindbrain at E13.5, extends to various brain regions including the cortex at E15.5 and displays a layer-associated expression in the cortex at E17.5. (B) Cdh13 is not localized in regions immunoreactive for Nestin (yellow arrow: area positive for Nestin). (C) Cdh13 is found in the hindbrain at E13.5 in two groups of fibers that extend longitudinally and transversally (D) Cdh13 immunoreactivity in the hindbrain is juxtaposed to Otx2 midbrain staining, delimiting the MHB at E13.5 (yellow dotted line: MHB). Orientation: sagittal. Scale bars in (A) 500 μm, in (B) 200 μm, in (C,D) 100 μm. Ctx, cortex; Hb, hindbrain; Mb, midbrain; Th, thalamus; OB, olfactory bulb.