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. 2017 Sep 26;11:307. doi: 10.3389/fncel.2017.00307

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Copyright © 2017 Forero, Rivero, Wäldchen, Ku, Kiser, Gärtner, Pennington, Waider, Gaspar, Jansch, Edenhofer, Resink, Blum, Sauer and Lesch.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cdh13 deficiency affects the cell density of the dorsal raphe at E17.5 and adulthood. Representative images of DR stained with 5-HT are shown for E17.5 (A) and adult (B) brains. A significantly higher density of serotonergic neurons is observed in Cdh13^−/− mice compared to wildtype controls at E17.5 (A), P = 0.0227 and adult (B), P = 0.0191 brains. N = 6 per genotype. Orientation in E17.5 sections: sagittal. Orientation in adult sections: coronal. Scale bar: 100 μm. Data are presented as mean ± s.e.m. ^*P < 0.05.