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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Free Radic Biol Med. 2017 Sep 1;112:578–586. doi: 10.1016/j.freeradbiomed.2017.08.026

Figure 2.

Figure 2

Loss of Nrf2 potentiates radiation-induced injury to alveolar type 2 cells. The thorax of male wild type and Nrf2 null mice was administered 0 (A, B) or 12 Gy (C, D) and the mice allowed to recover for 250 days. Wide field whole slide scanning microscopy was used to image Pdpn immunofluorescence (green) in order to identify alveolar type 1 cells. Spc immunofluorescence (red) in alveoli was used to identify and quantify alveolar type 2 cells. DAPI staining identifies nuclei. E) Quantification of Spc immunofluorescent cells per field, corrected for DAPI staining. White bar 100 μm.