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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Environ Int. 2017 Sep 5;108:212–220. doi: 10.1016/j.envint.2017.08.018

Table 4.

Percent differencea in relative telomere length by serum polychlorinated biphenyls (PCBs), ACHS participants

White African American


%Difference 95% CI %Difference 95% CI
PCB 99
 Per doubling of exposure 1.65 0.36 2.94 −0.05 −1.17 1.08
 <29.15 ppt Referent Referent
 29.15–71.60 ppt 2.31 −2.13 6.97 −2.42 −8.74 4.32
 71.60–189.60 ppt 4.67 −0.40 9.99 2.22 −4.68 9.63
 >189.60 ppt 8.84 1.77 16.41 −0.49 −7.20 6.71
p for trend 0.01 0.90
p for quadratic 0.69 0.64

PCB 105
 Per doubling of exposure 1.77 0.40 3.15 0.18 −0.57 0.93
 <7.75 ppt Referent Referent
 7.75–19.10 ppt 2.01 −2.43 6.66 1.30 −4.14 7.05
 19.10–58.20 ppt 3.46 −1.84 9.03 7.15 1.55 13.05
 >58.20 ppt 10.45 3.50 17.87 1.01 −4.12 6.41
p for trend 0.01 0.52
p for quadratic 0.25 0.03

PCB 118
 Per doubling of exposure 1.87 0.55 3.21 0.02 −1.07 1.12
 <49.60 ppt Referent Referent
 49.60–121.60 ppt 3.05 −1.60 7.93 −0.62 −6.71 5.87
 121.60–361.80 ppt 4.70 −0.69 10.38 6.05 −0.65 13.21
 >361.80 ppt 9.88 2.76 17.49 −0.24 −6.89 6.88
p for trend 0.01 0.88
p for quadratic 0.68 0.05

PCB 153
 Per doubling of exposure 1.75 0.26 3.26 −0.74 −1.94 0.47
 <278.75 ppt Referent Referent
 278.75–564.95 ppt 5.40 0.53 10.51 0.67 −6.06 7.89
 564.95–1398.50 ppt 7.08 1.64 12.82 2.39 −4.42 9.70
 >1398.50 ppt 7.62 0.57 15.15 −1.64 −8.26 5.46
p for trend 0.02 0.40
p for quadratic 0.19 0.15

PCB 167
 Per doubling of exposure 1.33 −0.20 2.89 −0.02 −1.20 1.17
 <10.88 ppt Referent Referent
 10.88–22.55 ppt 2.08 −3.00 7.43 1.87 −5.52 9.83
 22.55–57.20 ppt 3.82 −1.65 9.58 1.73 −5.27 9.24
 >57.20 ppt 8.58 1.54 16.10 −0.50 −7.45 6.98
p for trend 0.02 0.63
p for quadratic 0.57 0.33

PCB 183
 Per doubling of exposure 1.60 0.05 3.17 −0.13 −1.34 1.09
 <18.65 ppt Referent Referent
 18.65–39.25 ppt 2.59 −2.12 7.53 −0.53 −7.08 6.49
 39.25–93.40 ppt 5.79 0.42 11.45 3.08 −3.74 10.37
 >93.40 ppt 6.24 −0.80 13.79 0.43 −6.36 7.72
p for trend 0.03 0.83
p for quadratic 0.63 0.40

PCB 187
 Per doubling of exposure 1.22 −0.19 2.64 −0.26 −1.42 0.92
 <68.65 ppt Referent Referent
 68.65–159.50 ppt 5.56 0.42 10.95 2.52 −4.62 10.20
 159.50–394.75 ppt 7.67 1.96 13.70 4.38 −3.07 12.40
 >394.75 ppt 6.01 −0.98 13.49 0.73 −6.65 8.70
p for trend 0.04 0.73
p for quadratic 0.07 0.09

PCB 196
 Per doubling of exposure 1.21 −0.43 2.87 −0.24 −1.57 1.10
 <47.00 ppt Referent Referent
 47.00–110.85 ppt 6.30 0.53 12.40 0.45 −6.38 7.78
 110.85–249.35 ppt 8.59 2.02 15.59 −1.35 −8.59 6.46
 >249.35 ppt 9.23 1.32 17.76 −0.96 −8.11 6.73
p for trend 0.02 0.67
p for quadratic 0.16 0.93

PCB 199
 Per doubling of exposure 0.51 −0.96 1.99 −0.60 −1.82 0.65
 <51.75 ppt Referent Referent
 51.75–132.10 ppt 4.98 −0.78 11.07 −3.28 −9.85 3.77
 132.10–318.30 ppt 7.65 0.92 14.83 −4.34 −11.13 2.96
 >318.30 ppt 2.45 −4.78 10.23 −3.63 −10.50 3.76
p for trend 0.55 0.49
p for quadratic 0.01 0.33
a

Adjusted for age in years, age in years squared, total lipids, plate, smoking status, diabetes, education, sex, alcohol use in the past 30 days, and body mass index.