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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Gastroenterology. 2017 Jul 13;153(4):1068–1081.e7. doi: 10.1053/j.gastro.2017.07.002

Figure 7. Enteric glial elimination does not alter neuronal survival or the myenteric networks of nitrergic neurons and interstitial cells of Cajal.

Figure 7

(A–C) Immunoreactivities of neurofilament-H (NF-H) and the pan-neuronal marker, ANNA-1, in colons of Cre− (A) and Cre+ (B) mice revealed no difference in myenteric neuron number or the pattern of interganglionic connectives.

(D–F) Neuronal nitric oxide synthase (nNOS) immunostaining revealed no difference in nitrergic neuron density in the myenteric plexus of Cre− and Cre+ mice.

(G–H) SCFR immunoreactivity, a marker of interstitial cells of Cajal (ICC), revealed no difference in the ICC-MP network in Cre− and Cre+ mice.

Scale bars A–B=25μm; D–G=50μm