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The effect of live Salmonella typhimurium on occludin. Photographs illustrate staining for occludin in colonic biopsies from a patient with irritable bowel syndrome mounted in Ussing chambers. Biopsies were added buffer only (vehicle), Salmonella, Salmonella+vasoactive intestinal polypeptide (VIP)-receptor blocker (anti-VPACs) or Salmonella+ketotifen. After 30 min, biopsies were removed and stained for occludin by immunofluorescence.
