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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Gastroenterology. 2017 Jul 13;153(4):948–960.e3. doi: 10.1053/j.gastro.2017.06.051

Fig 4.

Fig 4

Staining of mast cell (MC)-tryptase (red) and vasoactive intestinal polypeptide receptors (VPACs) (green) in colon of a patient with irritable bowel syndrome (IBS) and healthy control (HC). Photographs show MCs±VPAC1 expressions in an IBS patient (A) and HC (B). Arrows indicate individual MC or VPAC1 staining and arrowheads indicate co-localization i.e. MCs expressing VPAC1 (C) Photograph showing MCs expressing VPAC2 (arrowheads) in IBS colon. Arrows indicate individual MC or VPAC2 staining. Overview photographs; 400Xmagnification, zoomed photographs; 1000X.