Table 2.
Baseline characteristics by PNPLA3 and TM6SF2 genotypes
| Genotype Group | 1 | 2 | 3 | 4 | 5 | 6 | 7 |
|---|---|---|---|---|---|---|---|
| PNPLA3 I148M (rs738409) | −/− (CC) | −/+ (CG) | +/+ (GG) | −/− (CC) | −/+ (CG) | +/+ (GG) | −/+ (CG) |
| TM6SF2 E167K (rs58542926) | −/− (CC) | −/− (CC) | −/− (CC) | −/+ (CT) | −/+ (CT) | −/+ (CT) | +/+ (TT) |
| Num (n, %) | 48 (28%) | 56 (32%) | 31 (19%) | 15 (9%) | 13 (7%) | 5 (3%) | 2 (1%) |
| Age | 50.8 ± 12.2 | 50.5 ± 13.7 | 48.5 ± 11.1 | 55.2 ± 10.6 | 47.5 ± 14.5 | 56.3 ± 13.3 | 37.0 ± 7.9 |
| Female (%) | 42% | 41% | 32% | 40% | 38% | 60% | 50% |
| Hispanics (%) | 6% | 11% | 35% | 0% | 15% | 0% | 50% |
| Diabetes (%) | 29% | 29% | 16% | 40% | 38% | 60% | 0% |
| Hypertension (%) | 48% | 45% | 35% | 60% | 54% | 60% | 50% |
| Dyslipidemia (%) | 50% | 36% | 35% | 47% | 54% | 60% | 0% |
| BMI (kg/m2) | 35.1 ± 6.2 | 34.6 ± 7.1 | 33.6 ± 5.9 | 33.0 ± 7.1 | 34.8 ± 5.6 | 30.7 ± 7.1 | 30.7 ± 7.1 |
| Waist Circumference (cm) | 111 ± 15 | 110 ± 15 | 108 ± 13 | 110 ± 18 | 108 ± 10.0 | 105 ± 15 | 108 |