(A & B), Final platelet or fibrin accumulation on TFlow bearing collagen surfaces at 100 s−1 measured by platelet or fibrin fluorescence at t = 15 min or just prior to full channel occlusion. (C & D), Final platelet or fibrin accumulation on TFhigh bearing collagen surfaces at 100 s−1 measured by platelet or fibrin fluorescence at t = 15 min or just prior to full channel occlusion. All data is ordered into three factor level categories (1–3%, 3–14% & > 14%) and compared to mean healthy subject final platelet or fibrin accumulation. Error bars are the standard deviation of 6 clotting events for each factor level category and 18 clotting events for seven healthy subjects. (** p < 0.01, * p < 0.05, ns: non-significant)