Table 3.
HRs for fracture based on individual FRAX® variables excluding BMD. All variables are defined as prescribed by FRAX®
| Hip fractures | Major osteoporotic fractures | |||||
| HR | 95% CI | p Value | HR | 95% CI | p Value | |
| Sex (men vs women) | 0.80 | 0.31 to 2.08 | 0.642 | 1.64 | 1.05 to 2.55 | 0.030 |
| Age (years) | 1.13 | 1.08 to 1.18 | <0.001 | 1.04 | 1.02 to 1.06 | <0.001 |
| BMI (kg/m2) | 1.05 | 0.97 to 1.14 | 0.204 | 0.98 | 0.94 to 1.01 | 0.206 |
| Previous fracture(yes/no) | 1.44 | 0.62 to 3.33 | 0.393 | 2.75 | 2.02 to 3.75 | <0.001 |
| Parent hip fractures (yes/no) | 3.29 | 1.31 to 8.19 | 0.011 | 3.51 | 2.48 to 4.98 | <0.001 |
| Current smoking (yes/no) | 0.95 | 0.29 to 3.12 | 0.931 | 1.32 | 0.87 to 2.01 | 0.196 |
| Glucocorticoids (yes/no) | 3.33 | 1.23 to 9.06 | 0.018 | 2.99 | 1.95 to 4.59 | <0.001 |
| Rheumatoid arthritis (yes/no) | 1.44 | 0.38 to 5.48 | 0.594 | 1.67 | 0.98 to 2.84 | 0.058 |
| Secondary osteoporosis (yes/no) | 1.34 | 0.56 to 3.22 | 0.514 | 1.61 | 1.17 to 2.23 | 0.004 |
| Alcohol three or more units day (yes/no) | 0.82 | 0.27 to 2.48 | 0.722 | 1.52 | 1.04 to 2.21 | <0.030 |
BMD, bone mineral density; BMI, body mass index.