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. 2017 May 9;7(5):e015409. doi: 10.1136/bmjopen-2016-015409

Table 1.

Planned inclusion and exclusion criteria

Inclusion criteria Exclusion criteria
Population Adult patients (>18 years) with a tremor diagnosis of confirmed aetiology
Unilateral or bilateral lesional functional neurosurgical intervention in a central neuroanatomical structure
By incisional (placement of a stylette, leukotome, cryosurgery or radiofrequency probe after skull opening) or incision-less (transcranially focused ultrasound (MRI-guided focused ultrasound), radiation energy (Gamma Knife) means
Cases subjected to lesional functional neurosurgery in more than one anatomical structure at the same time
Or stimulation techniques (deep brain stimulation)
Study design Randomised controlled trials, meta-analysis, case-control, prospective and retrospective case series
A minimum of five subjects included per cohort (indication/treatment)
Minimum follow-up of 2 months after the intervention
Studies reporting results from mixed aetiologies or mixed intervention (different anatomical targets or techniques)
Efficacy outcome Reporting tremor outcome on a validated tremor scale
Safety outcome Side effects after unilateral only interventions Cohorts including bilateral interventions
Type of publication Peer-reviewed articles without language restriction Letters, abstracts and editorials