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. 2017 Sep 24;7(9):e017266. doi: 10.1136/bmjopen-2017-017266

Table 2.

Cox proportional hazards models for the associations between socioeconomic and clinical variables with deaths from all causes in patients treated at the National Oncology Institute 2012–2015

Socioeconomic and clinical variables Crude HR Adjusted HR*
HR 95% CI HR 95% CI
Sex
 Female Reference Reference
 Male 0.93 (0.70 to 2.13) 0.67 (0.41 to 1.01)
Age
 45–64 years Reference Reference
 Less than 45 years 1.43 (0.96 to 2.13) 0.91 (0.53 to 1.58)
 65–74 years 0.90 (0.61 to 1.32) 0.66 (0.38 to 1.16)
 75 years or more 1.14 (0.78 to 1.68) 1.68 (0.91 to 3.10)
Social security status
 With social security Reference Reference
 Without social security 1.44† (1.01 to 2.05)† 2.02† (1.16 to 3.53)†
Employment status‡
 Formal employment Reference Reference
 Informal employment 1.04 (0.66 to 1.63) 1.29 (0.68 to 2.44)
 Retired/pensioner 0.87 (0.57 to 1.35) 1.48 (0.78 to 2.79)
 Unemployed 1.12 (0.77 to 1.65) 0.75 (0.40 to 1.44)
Marital status§
 Married/common-law marriage Reference Reference
 Single 1.06 (0.76 to 1.47) 0.87 (0.57 to 1.32)
 Widowed 0.72 (0.41 to 1.25) 0.57 (0.24 to 1.37)
Province
 Panama and Colon Reference Reference
 Veraguas and Cocle 0.87 (0.58 to 1.32) 0.86 (0.50 to 1.47)
 Herrera and Los Santos 0.62 (0.36 to 1.07) 0.71 (0.33 to 1.52)
 Other provinces 0.82 (0.48 to 1.41) 1.06 (0.48 to 2.33)
Anatomic location by endoscopy¶
 Non-cardia Reference Reference
 Cardia 1.30 (0.78 to 2.19) 0.94 (0.42 to 2.13)
 Overlapping 1.34 (0.99 to 1.83) 1.50 † (1.02 to 2.22)†
Histological type**
 Intestinal type Reference Reference
 Diffuse type 1.64† (1.13 to 2.40)† 0.79 (0.43 to 1.47)
 Mixed type 2.12† (1.31 to 3.44)† 1.57 (0.80 to 3.07)
Tumour grade††
 Well/moderately differentiated Reference Reference
 Poorly differentiated 1.91† (1.38 to 2.65)† 2.27† (1.22 to 4.22)†
Clinical stage
 I–III Reference Reference
 IV 4.37† (3.02 to 6.33)† 5.54† (3.38 to 9.08)†

*Adjustments were performed including all the covariates.

†p <0.05.

‡Employment status: one missing.

§Marital status: one missing.

¶Anatomic location: 11 missing.

**Histological type: 83 missing.

††Tumour grade: nine missing.