Table 3.

Risk of hip fracture for patients with stroke according to the duration of thiazide use

Duration of thiazide use	Patients (n)	Hip fractures	Person- years	Incidence rate*	Univariate model		Multivariate model†
					Crude HR (95% CI)	p Value	Adjusted HR (95% CI)	p Value
Non-user	3735	92	6596.4	13.9	1 (ref)		1 (ref)
1–90 days	1488	28	2710.1	10.3	0.76 (0.50 to 1.16)	0.206	0.73 (0.48 to 1.13)	0.160
91–365 days	1296	22	2477.5	8.9	0.69 (0.43 to 1.09)	0.111	0.69 (0.43 to 1.11)	0.127
>365 days	951	10	1887.3	5.3	0.42 (0.22 to 0.81)	0.010	0.41 (0.22 to 0.79)	0.008

*Per 1000 person-years.

†Multivariate Cox proportional hazard regression model, adjusting for all baseline characteristics (listed in table 1) and competing mortality.