Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Magn Reson Med. 2017 Mar 31;79(1):41–47. doi: 10.1002/mrm.26691

Figure 4.

Figure 4

Inter-subject variability study comparing MEGA-PRESS GABA+ versus improved MEGA-SPECIAL GABA estimates from (a) a 27 cc voxel in the occipital lobe of normal adults (N = 10). (b) GABA measurements were quantified relative to the creatine (Cre) signal. GABA+/Cre = 0.12 ± 0.013 (mean ± sd) and GABA/Cre = 0.07 ± 0.005. Acquisition parameters: 256 transients, 8.5 min acquisition. The coefficient-of-variation for GABA+/Cre was 11.2% compared to 7% for GABA/Cre. (c) Representative edited spectrum using MEGA-PRESS, and (d) representative edited spectrum using the improved MEGA-SPECIAL.