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MicroRNAs (miRNA) screening in primary hypothalamus neurons. CRH (A) and CRHR1 (B) mRNA in primary hypothalamus neurons transfected with miRNA agomir or its scramble control (n = 5) *vs. miR-NC-OE group (p < 0.05). CRH mRNA level (C) and CRH secretion (D) in primary hypothalamus neurons transfected with miRNA antagomir or its scramble control. The data are presented as the mean ± SD (n = 5) *vs. miR-NC-OE group in (A,B) or miR-NC-DE in (C,D) (p < 0.05).
