Table 1.
Baseline characteristics of patients with technically resectable, stage III/IV laryngeal or hypopharyngeal squamous cell carcinoma requiring total laryngectomy who were definitively treated with CRT
| Characteristic | No. (%) |
|---|---|
| Age, years | |
| Median | 66 |
| Range | 43–79 |
| Gender | |
| Male | 81 (95) |
| Female | 4 (5) |
| Primary site | |
| Hypopharynx | 50 (59) |
| Larynx | 35 (41) |
| T classificationa | |
| T2 | 19 (22) |
| T3 | 49 (58) |
| T4a | 17 (20) |
| N classificationa | |
| N0 | 26 (31) |
| N1 | 15 (17) |
| N2a/b/c | 0/29/15 (52) |
| Stagea | |
| III | 33 (39) |
| IV | 52 (61) |
| Radiation dose, Gy | |
| Median | 66 |
| Range | 64–70 |
| ≥66 Gy | 84 (99) |
| Chemotherapy cycle | |
| Median | 6 |
| Range | 2–6 |
| 6 cycles | 65 (76) |
| Duration between PET and CRT initiation, days | |
| Median | 25 |
| Range | 3–49 |
CRT, chemoradiotherapy; PET, positron emission tomography.
a
According to the 7th edition of the AJCC/UICC staging system.