Table 3.
Correlation between serum leucine‐rich α2‐glycoprotein‐1 (LRG1) and clinicopathological factors in 184 patients with gastric cancer
| Serum LRG1 | P‐value | ||
|---|---|---|---|
| Negative (<19.1 μg/mL) (n = 125) | Positive (≥19.1 μg/mL) (n = 59) | ||
| Age, years, median (range) | 65 (31–89) | 72 (37–87) | <0.0001 |
| Sex | 0.3517 | ||
| Male | 91 | 39 | |
| Female | 34 | 20 | |
| Location | 0.5665 | ||
| Upper | 36 | 19 | |
| Middle/lower | 89 | 40 | |
| Histological type | 0.3209 | ||
| Differentiated type | 58 | 32 | |
| Undifferentiated type | 67 | 27 | |
| Venous invasion | 0.0093 | ||
| Yes | 37 | 30 | |
| No | 83 | 29 | |
| Lymphatic invasion | 0.0009 | ||
| Yes | 56 | 43 | |
| No | 64 | 16 | |
| pT | 0.0038 | ||
| T1 | 68 | 16 | |
| T2 | 13 | 6 | |
| T3 | 21 | 18 | |
| T4 | 23 | 19 | |
| pN | <0.0001 | ||
| N0 | 89 | 24 | |
| N1–3 | 36 | 35 | |
| Pathological disease stage | 0.0010 | ||
| I | 77 | 20 | |
| II | 20 | 9 | |
| III | 21 | 21 | |
| IV | 7 | 9 | |
| LRG1 expression with IHC | 0.0014 | ||
| Score 0 | 5 | 3 | |
| Score 1 | 61 | 12 | |
| Score 2 | 29 | 16 | |
| Score 3 | 30 | 28 | |
| Helicobacter pylori | 0.0800 | ||
| Yes | 65 | 32 | |
| No | 60 | 27 | |
| CRP, median (range) | 0.04 (0.04–1.64) | 0.12 (0.04–5.11) | <0.0001 |
CRP, C‐reactive protein; IHC, immunohistochemical staining.