Table 1.
Characteristics of hemodialysis patients according to NT-proBNP levels.
| All patients N = 207 |
NT-proBNP (pg/mL) N = 207 | ||||
|---|---|---|---|---|---|
| <6243 n = 155 |
≥6243 n = 52 |
P | |||
| Age (y) | 207 | 64 ± 13 | 63 ± 14 | 65 ± 12 | 0.382 |
| Dialysis vintage (y) | 207 | 7.2 ± 0.4 | 6.9 ± 0.8 | 7.9 ± 0.9 | 0.342 |
| Dialysis vintage ≥ 3 y (%) | 207 | 73.4 | 69.0 | 86.5 | 0.013 |
| Sex (men) | 207 | 54.1 | 51.0 | 63.5 | 0.118 |
| Diabetes (%) | 207 | 41.5 | 46.5 | 26.9 | 0.013 |
| Previous CAD (%) | 207 | 9.7 | 9.0 | 11.5 | 0.597 |
| Hypertension (%) | 207 | 89.9 | 89.7 | 90.4 | 0.884 |
| Predialysis SBP (mmHg) | 207 | 146 ± 24 | 145 ± 24 | 149 ± 26 | 0.280 |
| Predialysis DBP (mmHg) | 207 | 81 ± 17 | 80 ± 14 | 83 ± 17 | 0.091 |
| Postdialysis SBP (mmHg) | 207 | 137 ± 26 | 135 ± 26 | 143 ± 27 | 0.048 |
| Postdialysis DBP (mmHg) | 207 | 76 ± 16 | 75 ± 16 | 77 ± 17 | 0.453 |
| Hemoglobin (g/dL) | 207 | 11.8 ± 1.5 | 11.9 ± 1.4 | 11.3 ± 1.6 | 0.008 |
| Serum sodium (mmol/L) | 207 | 139 ± 3 | 139 ± 2 | 138 ± 3 | 0.184 |
| IDWG (Kg) | 207 | 2.3 ± 1.0 | 2.4 ± 1.1 | 2.1 ± 0.8 | 0.014 |
| KT/V | 207 | 1.3 ± 0.2 | 1.3 ± 0.2 | 1.4 ± 0.2 | 0.475 |
| Nutritional supplementation | 207 | 26.6 | 22.6 | 38.5 | 0.025 |
| Nutritional parameters | |||||
| Body mass index (Kg/m2) | 207 | 26.1 ± 6.7 | 26.9 ± 6.9 | 23.8 ± 5.2 | 0.004 |
| Body mass index ≤ 23 Kg/m2 (%) | 207 | 35.7 | 29.0 | 55.8 | <0.001 |
| Serum albumin (g/L) | 207 | 38.2 ± 4.5 | 38.5 ± 4.5 | 37.3 ± 4.4 | 0.095 |
| Serum albumin ≤ 38 g/L (%) | 207 | 47.3 | 43.2 | 59.6 | 0.041 |
| Serum creatinine (µmol/L) | 207 | 884 ± 278 | 915 ± 275 | 793 ± 268 | 0.001 |
| Serum creatinine ≤ 818 µmol/L (%) | 207 | 41.1 | 34.2 | 61.5 | 0.001 |
| NPCR (g/kg/D) | 207 | 0.94 ± 0.21 | 0.96 ± 0.21 | 0.87 ± 0.21 | 0.010 |
| NPCR ≤ 0.8 g/kg/D (%) | 207 | 27.5 | 23.9 | 38.5 | 0.042 |
| Malnutrition (≥1 factor) (%) | 207 | 80.2 | 76.1 | 92.3 | 0.011 |
| PEW (≥3 factors) (%) | 207 | 16.9 | 11.0 | 34.6 | <0.001 |
| hsCRP > 5 (mg/L) | 207 | 48.5 | 40.6 | 71.2 | <0.001 |
|
| |||||
| Echocardiographic parameters | All patients N = 159 |
NT-proBNP (pg/mL) | |||
| <6243 N = 122 |
≥6243 N = 37 |
P | |||
|
| |||||
| LVEF (%) | 159 | 65.1 ± 8.5 | 66.3 ± 7.3 | 60.9 ± 10.9 | <0.001 |
| LVEF < 60 (%) | 159 | 13.8 | 10.7 | 24.3 | 0.035 |
| Left ventricular hypertrophy (%) | 159 | 40.3 | 38.5 | 45.9 | 0.420 |
Data in this table are presented as column percentages or mean ± SD. Significant P values are in bold.