Table 1.
Cell type | Cardiac resident | Self-renewal | Multipotent | Activation after injury | Improvement of cardiac function | Defined CPC | [Refs] | |
---|---|---|---|---|---|---|---|---|
Embryonic | Adult | |||||||
Side population | + | + | + | + | + | + | Yes | [6, 9, 11, 14, 29–45] |
c-kit+ cells | + | + | + | + | + | + | Yes | [6, 8–12, 35, 46–74] |
Sca-1 cells | + | + | + | + | + | + | Yes | [6, 9–13] |
Isl1 progenitors | + | ? | + | + | ? | ? | No | [9, 11, 47, 62, 88–99] |
Cardiospheres | + | + | + | + | ? | ? | No | [9, 11, 47, 62, 87, 88] |