Abundance of UV‐induced DNA lesions on all genes (Melanoma Gene, gray boxes) binned by the frequency of mutation in melanoma samples, available from the cancer browser in the COSMIC database (Forbes
et al,
2015).
n = number of genes per bin. Abundance is measured as fold change (FC) of binned genes/median of all genes in genome. Controls (Random Genes, white boxes) for each bin contain a random selection of the same number of genes as their corresponding bin. Percentage of genes with designated lamin‐associated domain (LAD) proximity is shown within each bin.