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. 2017 Sep 8;18(10):1837–1853. doi: 10.15252/embr.201744147

Figure 5. lncRNA‐PAGBC upregulates SOX4 and PIK3R3 levels.

Figure 5

  1. SOX4 mRNA (left) and protein (right) levels after the indicated plasmids were transfected into EH‐GB1 cells. Data are mean ± SD (n = 3).
  2. PIK3R3 mRNA (left) and protein (right) levels after the indicated plasmids were transfected into EH‐GB1 cells. Data are mean ± SD (n = 3).
  3. SOX4 mRNA (upper panel) and protein (lower panel) levels in stable NOZ and EH‐GB1 cell clones after transfection of the indicated miR‐133b inhibitors or mimics. Data are mean ± SD (n = 3).
  4. PIK3R3 mRNA (upper) and protein (lower) levels in stable NOZ and EH‐GB1 cell clones after transfection of the indicated miR‐511 inhibitors or mimics. Data are mean ± SD (n = 3).
  5. The correlation between lncRNA‐PAGBC transcript level and SOX4 (left) or PIK3R3 (right) mRNA transcript level was measured in 35 GBC tissues. The ΔC t values were subjected to Pearson correlation analysis.
  6. Scatterplots of the average staining scores for SOX4 (left) and PIK3R3 (right) expression in patients with low or high expression of lncRNA‐PAGBC.
Data information: *P < 0.05, **P < 0.01, ***P < 0.001 (Student's t‐test).Source data are available online for this figure.