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. 2017 Sep 4;6(9):e376. doi: 10.1038/oncsis.2017.75

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Copyright © 2017 The Author(s)

Oncogenesis is an open-access journal published by Nature Publishing Group. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Regulation between β-hCG, BRCA1 and TGFβRII in breast cancer. (a) Cell viability assay (MTS) of HCC1937 and MCF7 cells upon treating with TGFβRII inhibitor, SB-431542 for 48 h. (b) Summary of regulation between β-hCG and BRCA1 and possible tumorigenesis in BRCA1 defective breast tumors. *indicates the possible targets for effective inhibition of tumorigenesis in BRCA1 mutated cancer cells.