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. 2017 Sep 18;6(9):e379. doi: 10.1038/oncsis.2017.78

Table 2. Dissociation constants for the complexes between the Fbw7γ* peptide and Nter-NPM1 mutants.

Protein KD m)
Nter-NPM1 3.2±0.6
D36A 10.8±2.6
E37A 12.5±1.4
E39A 6.2±1.5
E93A 5.0±1.6
E121A 13.3±3.8
D36A-E39A 13.5±2.0
D36A-E93A 8.4±1.5
E39A-E93A 7.6±1.9
D36A-E39A-E93A 22.0±3.0
D36A-E37A-E39A-E93A 151.5±20.5
D36A-E39A-E93A-E121A 224.3±35.9
D36A-E37A-E39A-E93A-E121A 653.7±46.9