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. 2017 Sep 29;36:134. doi: 10.1186/s13046-017-0603-4

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Knockdown of Kindlin-2 inhibits Axin2 expression in HCC cells. a The microarray analysis indicated that Axin2 was significantly downregulated in LM3/LV-shK2 cells, with a fold change of 4.49. b Both quantitative real-time PCR and (c) Western blotting analyses revealed that Axin2 expression is decreased in Kindlin-2 knockout or knockdown cells but increased in Kindlin-2-overexpressing cells. ** represents P < 0.01